Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors-Reference-Cited by-同舟云学术

Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors

Published:2012-05 Issue:10 Volume:22 Page:3437-3440
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ágai-Csongor Éva,Domány György,Nógrádi Katalin,Galambos János,Vágó István,Keserű György Miklós,Greiner István,Laszlovszky István,Gere Anikó,Schmidt Éva,Kiss Béla,Vastag Mónika,Tihanyi Károly,Sághy Katalin,Laszy Judit,Gyertyán István,Zájer-Balázs Mária,Gémesi Larisza,Kapás Margit,Szombathelyi Zsolt

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

1. Novel sulfonamides having dual dopamine D2 and D3 receptor affinity show in vivo antipsychotic efficacy with beneficial cognitive and EPS profile

2. Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: I. neurochemical characterisation of RG-15

3. Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

4. Dopamine D3 receptor ligands—Recent advances in the control of subtype selectivity and intrinsic activity

5. Recent Advances in the Development of Dopamine D3 Receptor Antagonists: a Medicinal Chemistry Perspective

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