Discovery of new indole-based acylsulfonamide Nav1.7 inhibitors-Reference-Cited by-同舟云学术

Discovery of new indole-based acylsulfonamide Nav1.7 inhibitors

Published:2019-02 Issue:4 Volume:29 Page:659-663
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Wu Yong-Jin,Venables Brian,Guernon Jason,Chen Jie,Sit Sing-Yuen,Rajamani Ramkumar,Knox Ronald J.,Matchett Michele,Pieschl Rick L.,Herrington James,Bristow Linda J.,Meanwell Nicholas A.,Thompson Lorin A.,Dzierba Carolyn

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference34 articles.

1. The Nav1.7 sodium channel: from molecule to man;Dib-Hajj;Nat Rev Neurosci,2013

2. Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia;Yang;J Med Genet,2004

3. A SCN9A channelopathy causes congenital inability to experience pain;Cox;Nature,2006

4. A stop codon mutation in SCN9A causes lack of pain sensation;Ahmad;Hum Mol Genet,2007

5. Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations;Goldberg;Clin Genet,2007

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent advances in small molecule Nav 1.7 inhibitors for cancer pain management;Bioorganic Chemistry;2024-09

2. Alkoxyalkylation of Electron-Rich Aromatic Compounds;International Journal of Molecular Sciences;2024-06-26

3. N-Aryl Indoles as a Novel Class of Potent Na_V1.7 Inhibitors;ACS Medicinal Chemistry Letters;2023-05-24

4. Recent Advances in Biological Active Sulfonamide based Hybrid Compounds Part A: Two-Component Sulfonamide Hybrids;Current Medicinal Chemistry;2023-02

5. Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Nav1.7/ Nav1.8 blockers for the treatment of pain;Bioorganic & Medicinal Chemistry;2022-06