Synthesis and biological study of 2-amino-4-aryl-5-chloropyrimidine analogues as inhibitors of VEGFR-2 and cyclin dependent kinase 1 (CDK1)-Reference-Cited by-同舟云学术

Synthesis and biological study of 2-amino-4-aryl-5-chloropyrimidine analogues as inhibitors of VEGFR-2 and cyclin dependent kinase 1 (CDK1)

Published:2007-04 Issue:8 Volume:17 Page:2179-2183
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Huang Shenlin,Li Ronghua,Connolly Peter J.,Emanuel Stuart,Fuentes-Pesquera Angel,Adams Mary,Gruninger Robert H.,Seraj Jabed,Middleton Steven A.,Davis Jeremy M.,Moffat David F.C.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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5. Preclinical and clinical development of the oral multikinase inhibitor sorafenib in cancer treatment

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