Simultaneous determination of amlodipine, valsartan and hydrochlorothiazide by LC–ESI-MS/MS and its application to pharmacokinetics in rats

Author:

Gadepalli Shankar Ganesh,Deme Pragney,Kuncha Madhusudana,Sistla Ramakrishna

Funder

JNTUK, Kakinada

Publisher

Elsevier BV

Subject

Analytical Chemistry,Electrochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Pharmacy

Reference34 articles.

1. Development and validation of a highly sensitive and robust LC–ESI-MS/MS method for simultaneous quantitation of simvastatin acid, amlodipine and valsartan in human plasma: application to a clinical pharmacokinetic study;Ramani;Biomed. Chromatogr.,2009

2. Valsartan/hydrochlorothiazide: a review of its pharmacology, therapeutic efficacy and place in the management of hypertension;Wellington;Drugs,2002

3. Crystal Phend, Staff Writer, FDA Approves Triple-Drug Antihypertensive Polypill, MedPageToday,Washington, (〈http://www.medpagetoday.com/ProductAlert/Prescriptions/14032〉), May 1 2009.

4. Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research(CDER), Exforge HCT (amlodipine/valsartan/hydrochlorothiazide) Tablets, (〈http://www.fda.gov/Safety/MedWatch/SafetyInformation/ucm262227.htm〉), 2012.

5. H.C.T. Exforge, Rx List, (〈http://www.rxlist.com/exforge-hct-drug.htm〉), September 18 2013.

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