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Neural differentiation of fragile X human embryonic stem cells reveals abnormal patterns of development despite successful neurogenesis

  • Published:2013-02 Issue:1 Volume:374 Page:32-45
  • ISSN:0012-1606
  • Container-title:Developmental Biology
  • language:en
  • Short-container-title:Developmental Biology

Author:

Telias Michael,Segal Menahem,Ben-Yosef Dalit

Funder

Chief Scientist Office of the Israel Ministry of Health

Israel Science Foundation

Tel-Aviv Sourasky Medical Center

Publisher

Elsevier BV

Subject

Cell Biology,Developmental Biology,Molecular Biology

Reference58 articles.

1. Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain;Abitbol;Nat. Genet.,1993

2. Correlates across the structural, functional, and molecular phenotypes of fragile X syndrome;Beckel-Mitchener;Ment. Retard. Dev. Disabil. Res. Rev.,2004

3. Female sex bias in human embryonic stem cell Lines;Ben-Yosef;Stem Cells Dev.,2011

4. The pathophysiology of fragile X (and what it teaches us about synapses);Bhakar;Annu. Rev. Neurosci.,2012

5. Normal neurogenesis but abnormal gene expression in human fragile X cortical progenitor cells;Bhattacharyya;Stem. Cells Dev.,2008
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