Large-scale randomized evidence: Large, simple trials and overviews of trials

Author:

Peto Richard,Collins Rory,Gray Richard

Publisher

Elsevier BV

Subject

Epidemiology

Reference28 articles.

1. Randomized trial of intravenous atenolol among 16,027 cases of suspected acute myocardial infarction. ISIS-1;Lancet,1986

2. Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction. ISIS-2;Lancet,1988

3. ISIS-3: A randomized trial of streptokinase vs tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41,299 cases of suspected acute myocardial infarction;Lancet,1992

4. Fourth International Study of Infarct Survival: protocol for a large, simple study of the effects of oral mononitrate, of oral captopril, and of intravenous magnesium;Am J Cardiol,1991

5. Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction;Lancet,1986

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