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Biased signaling by human follicle-stimulating hormone variants

  • Published:2025-04 Issue: Volume:268 Page:108821
  • ISSN:0163-7258
  • Container-title:Pharmacology & Therapeutics
  • language:en
  • Short-container-title:Pharmacology & Therapeutics

Author:

Ulloa-Aguirre Alfredo,Zariñán Teresa,Dias James A.,Kumar T. Rajendra,Bousfield George R.

Funder

National Autonomous University of Mexico Directorate General of Academic Staff Affairs

National Institutes of Health

Universidad Nacional Autónoma de México

Coordinación de la Investigación Científica

Foundation for the National Institutes of Health

Publisher

Elsevier BV

Reference140 articles.

1. Generating FSH antagonists and agonists through immunization against FSH receptor N-terminal decapeptides;Abdennebi;Journal of Molecular Endocrinology,1999

2. Critical involvement of the hinge region of the follicle-stimulating hormone receptor in the activation of the receptor;Agrawal;The Journal of Biological Chemistry,2009

3. Differential FSH glycosylation modulates FSHR oligomerization and subsequent cAMP signaling;Agwuegbo;Frontiers in Endocrinology (Lausanne),2021

4. Effect of different FSH isoforms on cyclic-AMP production by mouse cumulus-oocyte-complexes: a time course study;Andersen;Molecular Human Reproduction,2001

5. Are circulating gonadotropin isoforms naturally occurring biased agonists? Basic and therapeutic implications;Arey;Reviews in Endocrine & Metabolic Disorders,2011

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