Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1α pathway

Author:

Li Xuechen,Zhuge Zhengbing,Carvalho Lucas Rannier R.A.,Braga Valdir A.,Lucena Ricardo BarbosaORCID,Li Shuijie,Schiffer Tomas A.,Han Huirong,Weitzberg Eddie,Lundberg Jon O.,Carlström MattiasORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Biochemistry,Clinical Biochemistry

Reference30 articles.

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2. Renal inflammation and fibrosis: a double-edged sword;Black;J. Histochem. Cytochem.,2019

3. Renal fibrosis in 2015: understanding the mechanisms of kidney fibrosis;Zhou;Nat. Rev. Nephrol.,2016

4. Targeting energy pathways in kidney disease: the roles of Sirtuins, AMPK, and PGC1alpha;Clark;Kidney Int.,2020

5. Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development;Kang;Nat. Med.,2015

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