New series of 6-substituted coumarin derivatives as effective factor Xa inhibitors: Synthesis, in vivo antithrombotic evaluation and molecular docking-Reference-Cited by-同舟云学术

New series of 6-substituted coumarin derivatives as effective factor Xa inhibitors: Synthesis, in vivo antithrombotic evaluation and molecular docking

Published:2014-02 Issue: Volume:52 Page:31-43
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Amin Kamelia M.,Abdel Gawad Nagwa M.,Abdel Rahman Doaa E.,El Ashry Mohamed K.M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference62 articles.

1. Triggers, targets and treatments for thrombosis

2. Heparin

3. Oral Anticoagulants: Mechanism of Action, Clinical Effectiveness, and Optimal Therapeutic Range

4. Antithrombotic Effects and Bleeding Time of Thrombin Inhibitors and Warfarin in the Rat

5. Discovery of the Novel Antithrombotic Agent 5-Chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): An Oral, Direct Factor Xa Inhibitor

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