Discovery of highly potent HDAC8 PROTACs with anti-tumor activity
Author:
Funder
China Scholarship Council
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry
Reference56 articles.
1. Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight;Ho;J Med Chem,2020
2. Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders;Falkenberg;Nat Rev Drug Discov,2014
3. Epigenetic Therapies for Cancer;Bates;N Engl J Med,2020
4. Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia;Bishton;Blood,2011
5. Clinical Toxicities of Histone Deacetylase Inhibitors;Subramanian;Pharmaceuticals (Basel),2010
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Integrated molecular modeling and dynamics approaches revealed the mechanism of selective inhibition of HDAC6/8;Journal of Biomolecular Structure and Dynamics;2023-10-23
2. Are inhibitors of histone deacetylase 8 (HDAC8) effective in hematological cancers especially acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL)?;European Journal of Medicinal Chemistry;2023-10
3. Targeting reversible post-translational modifications with PROTACs: a focus on enzymes modifying protein lysine and arginine residues;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-09-04
4. Establishment and verification of a nomogram to predict risk and prognostic factors of triple-negative breast cancer with organ metastasis based on the SEER cohort study;2023-08-05
5. PROTAC chemical probes for histone deacetylase enzymes;RSC Chemical Biology;2023
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3