Physiologically based pharmacokinetic modeling to predict the clinical effect of azole antifungal agents as CYP3A inhibitors on azelnidipine pharmacokinetics

Author:

Watanabe Akiko,Kotsuma Masakatsu

Funder

Daiichi Sankyo Company

Daiichi-Sankyo

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

Reference39 articles.

1. [Pharmacological profiles and clinical effects of azelnidipine, a long-acting calcium channel blocker];Sada;Nihon Yakurigaku Zasshi,2003

2. Antihypertensive effects of CS-905, a novel dihydropyridine Ca++ channel blocker;Oizumi;Jpn J Pharmacol,1989

3. Daiichi Sankyo Co., Ltd. Calblock® (azelnidipine) package Insert. https://www.data-index.co.jp/dragdata/pdf/2/430574_2149043F1020_2_14.pdf [In Japanese] 2021; ver. 2 [accessed 25 Feb 2023]..

4. Drug interactions between nine antifungal agents and drugs metabolized by human cytochromes P450;Niwa;Curr Drug Metabol,2014

5. Duration of effect of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin;Lilja;Clin Pharmacol Ther,2000

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