Novel beta-glucocerebrosidase chaperone compounds identified from cell-based screening reduce pathologically accumulated glucosylsphingosine in iPS-derived neuronal cells

Author:

Naito Yusuke,Sakamoto Sou,Kojima Takuto,Homma Misaki,Tanaka Maiko,Matsui HidekiORCID

Publisher

Elsevier BV

Subject

Molecular Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Reference34 articles.

1. Lysosomal degradation of membrane lipids;Kolter;FEBS Lett,2010

2. Gaucher disease: insights from a rare Mendelian disorder;Sidransky;Discov Med,2012

3. Phenotype, diagnosis, and treatment of Gaucher's disease;Grabowski;Lancet,2008

4. Cost-effectiveness of enzyme replacement therapy for type 1 Gaucher disease;van Dussen;Orphanet J Rare Dis,2014

5. LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase;Reczek;Cell,2007

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