IL-12 inhibits glucocorticoid-induced T cell apoptosis by inducing GMEB1 and activating PI3K/Akt pathway

Author:

Kawabe Kiyokazu,Lindsay Daniel,Braitch Manjit,Fahey Angela J.,Showe Louise,Constantinescu Cris S.

Publisher

Elsevier BV

Subject

Hematology,Immunology,Immunology and Allergy

Reference37 articles.

1. Cell-specific regulation of apoptosis by glucocorticoids: implication to their anti-inflammatory action;Amsterdam;Biochem. Pharmacol.,2002

2. Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12;Bacon;J. Exp. Med.,1995

3. Glucocorticoids increase CD4(+)CD25(high) cell percentage and Foxp3 expression in patients with multiple sclerosis;Braitch;Acta Neurol. Scand.,2008

4. Activation-induced cell death;Budd;Curr. Opin. Immunol.,2001

5. Recent insights into the mechanism of glucocorticosteroid-induced apoptosis;Distelhorst;Cell Death Differ.,2002

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