Cleaning of direct compression continuous manufacturing equipment through displacement of API residues by excipients

Author:

Patel Dhavalkumar S.ORCID,Méndez RafaelORCID,Romañach Rodolfo J.ORCID

Funder

Economic Development Administration

Puerto Rico Science Technology and Research Trust

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference31 articles.

1. Loss-in-weight feeding, powder flow and electrostatic evaluation for direct compression hydroxypropyl methylcellulose (HPMC) to support continuous manufacturing;Allenspach;Int. J. Pharm.,2021

2. Impact of blend properties and process variables on the blending performance;Bekaert;Int. J. Pharm.,2022

3. In-depth analysis of the long-term processability of materials during continuous feeding;Bekaert;Int. J. Pharm.,2022

4. Continuous direct compression: Development of an empirical predictive model and challenges regarding PAT implementation;Bekaert;Int J Pharm X,2022

5. Implementation of a Fully Integrated Continuous Manufacturing Line for Direct Compression and Coating at a Commercial Pharmaceutical Facility - Part 1: Operational Considerations and Control Strategy;Conway;Int. J. Pharm.,2023

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