In vitro behavior of a phosphate ester prodrug of amprenavir in human intestinal fluids and in the Caco-2 system: Illustration of intraluminal supersaturation-Reference-Cited by-同舟云学术

In vitro behavior of a phosphate ester prodrug of amprenavir in human intestinal fluids and in the Caco-2 system: Illustration of intraluminal supersaturation

Published:2007-05 Issue:2 Volume:336 Page:302-309
ISSN:0378-5173
Container-title:International Journal of Pharmaceutics
language:en
Short-container-title:International Journal of Pharmaceutics

Author:

Brouwers Joachim,Tack Jan,Augustijns Patrick

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference18 articles.

1. Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: a case study with amprenavir;Brouwers;J. Pharm. Sci.,2006

2. Effect of P-glycoprotein modulators on alkaline phosphatase activity in cultured rat hepatocytes;Calhau;Cell Physiol. Biochem.,2000

3. Fosamprenavir: a review of its use in the management of antiretroviral therapy-naive patients with HIV infection;Chapman;Drugs,2004

4. Alkaline phosphatase (EC 3.1.3. 1) in serum is inhibited by physiological concentrations of inorganic phosphate;Coburn;J. Clin. Endocrinol. Metab.,1998

5. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers;Falcoz;J. Clin. Pharmacol.,2002

Cited by 64 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An Eco-Friendly RP-HPLC Method Development and Validation for Quantification of Favipiravir in Bulk and Tablet Dosage Form Followed by Forced Degradation Study;Journal of Chromatographic Science;2024-01-23

2. Enzymatic prodrug degradation in the fasted and fed small intestine: In vitro studies and interindividual variability in human aspirates;International Journal of Pharmaceutics;2024-01

3. Developing an adult stem cell derived microphysiological intestinal system for predicting oral prodrug bioconversion and permeability in humans;Lab on a Chip;2024

4. Impact of prandial state on luminal and permeation-behavior of fosamprenavir oral suspension studied by in vitro tools: Solubility-, bioconversion- and permeation- studies in biomimetic media;Journal of Drug Delivery Science and Technology;2023-12

5. Challenges in Permeability Assessment for Oral Drug Product Development;Pharmaceutics;2023-09-28