Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial

Author:

Miguel Jesus San,Weisel Katja,Moreau Philippe,Lacy Martha,Song Kevin,Delforge Michel,Karlin Lionel,Goldschmidt Hartmut,Banos Anne,Oriol Albert,Alegre Adrian,Chen Christine,Cavo Michele,Garderet Laurent,Ivanova Valentina,Martinez-Lopez Joaquin,Belch Andrew,Palumbo Antonio,Schey Stephen,Sonneveld Pieter,Yu Xin,Sternas Lars,Jacques Christian,Zaki Mohamed,Dimopoulos Meletios

Publisher

Elsevier BV

Subject

Oncology

Reference31 articles.

1. Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib therapy: a multicentre International Myeloma Working Group study;Kumar;Leukemia,2012

2. Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma;Quach;Leukemia,2010

3. MM-008 trial: Pharmacokinetics (PK) and tolerability of pomalidomide plus lowdose dexamethasone (POM plus LoDEX) in relapsed/refractory multiple myeloma (RRMM) patients with renal impairment (RI);Matous;J Clin Oncol,2013

4. Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapsed or refractory multiple myeloma;Schey;J Clin Oncol,2004

5. Alternate day pomalidomide retains anti-myeloma effect with reduced adverse events and evidence of in vivo immunomodulation;Streetly;Br J Haematol,2008

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