The Vitotox and ToxTracker assays: A two-test combination for quick and reliable assessment of genotoxic hazards

Author:

Ates Gamze,Favyts Dorien,Hendriks Giel,Derr RemcoORCID,Mertens Birgit,Verschaeve Luc,Rogiers Vera,Y. Doktorova Tatyana

Funder

Vrije Universiteit Brussel and the Scientific Institute of Public Health (WIV-ISP), Belgium

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference35 articles.

1. Reflections on the origins and evolution of genetic toxicology and the Environmental Mutagen Society;Wassom;Environ. Mol. Mutagen.,2010

2. A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins;Kirkland;Mutat. Res. – Genet. Toxicol. Environ. Mutagen.,2011

3. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. I. Sensitivity, specificity and relative predicticity;Kirkland;Mutat. Res. – Genet. Toxicol. Environ. Mutagen.,2005

4. Retrospective analysis of the mutagenicity/genotoxicity data of the cosmetic ingredients present on the Annexes of the Cosmetic EU legislation (2000–12);Ates;Mutagenesis,2014

5. OECD, Test No. 471: Bacterial Reverse Mutation Test, OECD Guidel. Test. Chem. Sect. 4. (1997) 11. http://www.oecd-ilibrary.org/environment/test-no-471-bacterial-reverse-mutation-test_9789264071247-en (accessed 29.08.16).

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