Synthesis and biological evaluation of all A-ring stereoisomers of 5,6-trans-2-methyl-1,25-dihydroxyvitamin D3 and their 20-epimers: possible binding modes of potent A-ring analogues to vitamin D receptor-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of all A-ring stereoisomers of 5,6-trans-2-methyl-1,25-dihydroxyvitamin D3 and their 20-epimers: possible binding modes of potent A-ring analogues to vitamin D receptor

Published:2001-11 Issue:11 Volume:8 Page:1011-1024
ISSN:1074-5521
Container-title:Chemistry & Biology
language:en
Short-container-title:Chemistry & Biology

Author:

Fujishima Toshie,Konno Katsuhiro,Nakagawa Kimie,Tanaka Maki,Okano Toshio,Kurihara Masaaki,Miyata Naoki,Takayama Hiroaki

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference46 articles.

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3. Structure-function relationships in the vitamin D endocrine system;Bouillon;Endocr. Rev.,1995

4. 20-Epi-vitamin D3 analogues: A novel class of potent regulators of cell growth and immune responses;Binderup;Biochem. Pharmacol.,1991

5. Increased biological activity of 20-epi-1,25-dihydroxyvitamin D3 is due to reduced catabolism and altered protein binding;Dilworth;Biochem. Pharmacol.,1994

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