Application of the Steric Mass Action formalism for modeling under high loading conditions: Part 2. Investigation of high loading and column overloading effects-Reference-Cited by-同舟云学术

Application of the Steric Mass Action formalism for modeling under high loading conditions: Part 2. Investigation of high loading and column overloading effects

Published:2022-08 Issue: Volume:1676 Page:463266
ISSN:0021-9673
Container-title:Journal of Chromatography A
language:en
Short-container-title:Journal of Chromatography A

Author:

Seelinger Felix,Wittkopp Felix,von Hirschheydt Thomas,Frech Christian

Funder

Roche

Publisher

Elsevier BV

Subject

Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry

Reference33 articles.

1. Application of the steric mass action formalism for modeling under high loading conditions: part 1. Investigation of the influence of pH on the steric shielding factor;Seelinger;J. Chromatogr. A,2022

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3. Mechanistic modeling of ion-exchange process chromatography of charge variants of monoclonal antibody products;Kumar;J. Chromatogr. A,2015

4. Evaluation of differences between dual salt-pH gradient elution and mono gradient elution using a thermodynamic model: simultaneous separation of six monoclonal antibody charge and size variants on preparative-scale ion exchange chromatographic resin;Lee;Biotechnol. Prog.,2018

5. Simulation model for overloaded monoclonal antibody variants separations in ion-exchange chromatography;Guélat;J. Chromatogr. A,2012

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4. Anti-Langmuir elution behavior of a bispecific monoclonal antibody in cation exchange chromatography: Mechanistic modeling using a pH-dependent Self-Association Steric Mass Action isotherm;Journal of Chromatography A;2023-01