Reprogramming Captures the Genetic and Tumorigenic Properties of Neurofibromatosis Type 1 Plexiform Neurofibromas

Author:

Carrió Meritxell,Mazuelas Helena,Richaud-Patin Yvonne,Gel Bernat,Terribas Ernest,Rosas Imma,Jimenez-Delgado Senda,Biayna Josep,Vendredy Leen,Blanco Ignacio,Castellanos Elisabeth,Lázaro Conxi,Raya Ángel,Serra EduardORCID

Funder

Johns Hopkins University School of Medicine

Neurofibromatosis Therapeutic Acceleration Program

Spanish Ministry of Science and Innovation

Carlos III Health Institute

FEDER

Government of Catalonia

CERCA

Spanish Association Against Cancer

NTAP Cell Culture Initiative

Publisher

Elsevier BV

Subject

Cell Biology,Developmental Biology,Genetics,Biochemistry

Reference54 articles.

1. Elucidating the impact of neurofibromatosis-1 germline mutations on neurofibromin function and dopamine-based learning;Anastasaki;Hum. Mol. Genet.,2015

2. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors;Ban;Proc. Natl. Acad. Sci. U S A,2011

3. Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors;Beert;Genes Chromosomes Cancer,2011

4. Melanoma-derived iPCCs show differential tumorigenicity and therapy response;Bernhardt;Stem Cell Rep.,2017

5. Cell of origin and the contribution of microenvironment in NF1 tumorigenesis and therapeutic implications;Buchstaller,2012

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