Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling

Author:

Bertholet Ambre M.,Kazak Lawrence,Chouchani Edward T.,Bogaczyńska Marta G.,Paranjpe Ishan,Wainwright Gabrielle L.,Bétourné Alexandre,Kajimura Shingo,Spiegelman Bruce M.,Kirichok Yuriy

Funder

NIH

JPB Foundation

Canadian Institutes of Health Research

Human Frontier Science Program

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Physiology

Reference49 articles.

1. UCP1: A transporter for H(+) and fatty acid anions;Bertholet;Biochimie,2017

2. Human brown adipose tissue: what we have learned so far;Betz;Diabetes,2015

3. 108-pS channel in brown fat mitochondria might Be identical to the inner membrane anion channel;Borecký;J. Biol. Chem.,1997

4. Brown adipose tissue: function and physiological significance;Cannon;Physiol. Rev.,2004

5. Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1;Chouchani;Nature,2016

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