Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

Author:

Palsson-McDermott Eva M.,Curtis Anne M.,Goel Gautam,Lauterbach Mario A.R.,Sheedy Frederick J.,Gleeson Laura E.,van den Bosch Mirjam W.M.,Quinn Susan R.,Domingo-Fernandez Raquel,Johnston Daniel G.W.,Jiang Jian-kang,Israelsen William J.,Keane Joseph,Thomas Craig,Clish Clary,Vander Heiden Matthew,Xavier Ramnik J.,O’Neill Luke A.J.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Physiology

Reference37 articles.

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4. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis;Bafica;J. Exp. Med.,2005

5. Evaluation of substituted N,N’-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase;Boxer;J. Med. Chem.,2010

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