Thalidomide can costimulate or suppress CD4+ cells' ability to incorporate [H3]-thymidine—dependence on the primary stimulant

Author:

Shannon Edward J,Sandoval Felipe G

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference22 articles.

1. Immunomodulation by thalidomide: systemic review of the literature and of unpublished observations;Zwingenberger;J. Inflam.,1996

2. Thalidomide increases the synthesis of IL-2 in cultures of human mononuclear cells stimulated with Concanavalin-A, staphylococcal enterotoxin A, and purified protein derivative;Shannon;Immunopharmacology,1995

3. Hydrolysis of thalidomide abrogates its ability to enhance mononuclear cell synthesis of IL-2 as well as its ability to suppress the synthesis of TNF-α;Shannon;Immunopharmacology,1997

4. Thalidomide prolonged graft survival in a rat cardiac transplant moded but had no inhibitory effect on lymphocyte function in vitro;Östraat;Transpl. Immunol.,1996

5. Does thalidomide affect IL-2 response and production?;Fennandez;Exp. Hematol.,1995

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