Chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: Pooled analysis of the CAO/ARO/AIO-12 and the OPRA randomized phase 2 trials

Author:

Fokas Emmanouil,Williams Hannah,Diefenhardt Markus,Lin Sabrina,Qin Li-Xuan,Piso Pompiliu,Dapper Hendrik,Germer Christoph-Thomas,Grützmann Robert,Tim Friede J.,Joshua Smith J.,Saltz Leonard B.,Wu Abraham J.,Weiser Martin R.,Omer Dana,Ghadimi Michael,Hofheinz Ralf-Dieter,Garcia-Aguilar Julio,Rödel Claus

Funder

Deutsche Krebshilfe

National Cancer Institute

Universität zu Köln

Publisher

Elsevier BV

Reference17 articles.

1. Outcome measures in multimodal rectal cancer trials;Fokas;Lancet Oncol,2020

2. Adoption of total neoadjuvant therapy for locally advanced rectal cancer;Cercek;JAMA Oncol,2018

3. Playing With dynamite? A cautious assessment of TNT;Shi;J Clin Oncol,2021

4. Assessment of a watch-and-wait strategy for rectal cancer in patients with a complete response after neoadjuvant therapy;Smith;JAMA Oncol,2019

5. Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial;Bahadoer;Lancet Oncol,2020

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