OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis

Author:

Astorgues-Xerri Lucile,Riveiro Maria E.,Tijeras-Raballand Annemilaï,Serova Maria,Rabinovich Gabriel A.,Bieche Ivan,Vidaud Michel,de Gramont Armand,Martinet Mathieu,Cvitkovic Esteban,Faivre Sandrine,Raymond Eric

Funder

Foundation Nelia & Amadeo Barleta

Association d’Aide à la Recherche & à l’Enseignement en Cancérologie

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference46 articles.

1. Galectins. Structure and function of a large family of animal lectins;Barondes;J Biol Chem,1994

2. Galectinomics: finding themes in complexity;Cooper;Biochim Biophys Acta,2002

3. Galectins as modulators of tumour progression;Liu;Nat Rev Cancer,2005

4. Galectin-1: a small protein with major functions;Camby;Glycobiology,2006

5. Galectin-1 is a novel functional receptor for tissue plasminogen activator in pancreatic cancer;Roda;Gastroenterology,2009

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