Solution structure ensemble of human obesity-associated protein FTO reveals druggable surface pockets at the interface between the N- and C-terminal domain
Author:
Funder
National Institute of General Medical Sciences
National Institutes of Health
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference61 articles.
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2. Catalytic mechanisms of Fe(II)- and 2-Oxoglutarate-dependent oxygenases;Martinez;J. Biol. Chem.,2015
3. Nucleic acid oxidation in DNA damage repair and epigenetics;Zheng;Chem. Rev.,2014
4. Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO;Jia;FEBS Lett.,2008
5. Differential m6A, m6Am, and m1A demethylation mediated by FTO in the cell nucleus and cytoplasm;Wei;Mol. Cell,2018
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