Novel MRPL13-ALK and PPP1CB-ALK Double Fusion As a Potential Mechanism of Acquired Resistance to First-Line Osimertinib in EGFR-Mutant High-Grade Neuroendocrine Tumor of the Lung

Author:

Jiao Yuyan,Liu Ming,Luo Ningning,Guo Hao,Li Jianzhe

Publisher

Elsevier BV

Subject

Pulmonary and Respiratory Medicine,Oncology

Reference6 articles.

1. Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer;Leonetti;Br J Cancer,2019

2. Acquired ALK and RET gene fusions as mechanisms of resistance to osimertinib in EGFR-mutant lung cancers;Offin;JCO Precis Oncol,2018

3. Receptor tyrosine kinase fusions and BRAF kinase fusions are rare but actionable resistance mechanisms to EGFR tyrosine kinase inhibitors;Schrock;J Thorac Oncol,2018

4. Catalog of 5’ Fusion Partners in ALK-positive NSCLC circa 2020;Ou;JTO Clin Res Rep,2020

5. Receptor tyrosine kinase fusions as an actionable resistance mechanism to EGFR TKIs in EGFR-mutant non-small-cell lung cancer;Zhu;Trends Cancer,2019

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