Cystic fibrosis transmembrane conductance regulator ameliorates lipopolysaccharide-induced acute lung injury by inhibiting autophagy through PI3K/AKT/mTOR pathway in mice

Author:

Sui Hongshu,Luo Mingjiu,Miao Yaya,Cheng Wanjing,Wen Shan,Zhao Bohou,Li Yuming,Qiao Zengyun,Liu Yaling,Xu Changlong

Funder

National Natural Science Foundation of China

National Key R&D Program of China

Funds of Shandong Double Tops Program

Guangxi Natural Science Fund project

Publisher

Elsevier BV

Subject

Pulmonary and Respiratory Medicine,Physiology,General Neuroscience

Reference36 articles.

1. Recombinant chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) protects against LPS-induced lung injury in mice;Ali;Clin. Immunol.,2018

2. Olive leaf extract attenuates inflammatory activation and DNA damage in human arterial endothelial cells;Burja;Front. Cardiovasc. Med.,2019

3. The PI3K/Akt/mTOR pathway is involved in CVB3-induced autophagy of HeLa cells;Chang;Int. J. Mol. Med.,2017

4. The protective effect of CDDO-Me on lipopolysaccharide-induced acute lung injury in mice;Chen;Int. Immunopharmacol.,2015

5. 3-Methyladenine and dexmedetomidine reverse lipopolysaccharide-induced acute lung injury through the inhibition of inflammation and autophagy;Ding;Exp. Ther. Med.,2018

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