Pharmacokinetics and exposure-efficacy relationships of omalizumab in patients with nasal polyps

Author:

Zhu Rui,Owen RyanORCID,Wilkins JustinORCID,Schoemaker RikORCID,Tian Xianbin,Gautier Aurelie,She Gaohong,Vadhavkar Shweta,Cheu MelissaORCID,Wong KitORCID,Omachi Theodore A.,Putnam Wendy S.ORCID,Quartino Angelica L.

Funder

Genentech

Publisher

Elsevier BV

Subject

Pharmacology (medical),Biochemistry, medical,Pulmonary and Respiratory Medicine

Reference33 articles.

1. Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody;MacGlashan;J Immunol,1997

2. Effect of omalizumab treatment on peripheral eosinophil and T-lymphocyte function in patients with allergic asthma;Noga;J Allergy Clin Immunol,2006

3. Omalizumab treatment downregulates dendritic cell FcepsilonRI expression;Prussin;J Allergy Clin Immunol,2003

4. The effects of omalizumab on IgE-induced cytokine synthesis by asthmatic airway smooth muscle cells;Roth;Ann Allergy Asthma Immunol,2010

5. Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma;Djukanovic;Am J Respir Crit Care Med,2004

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