Prediction of pH-Dependent Drug-Drug Interactions for Basic Drugs Using Physiologically Based Biopharmaceutics Modeling: Industry Case Studies
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference46 articles.
1. Prevalence of acid-reducing agents (ARA) in cancer populations and ARA drug-drug interaction potential for molecular targeted agents in clinical development;Smelick;Mol Pharm,2013
2. Insights into the future of gastric acid suppression;DeVault;Nat Rev Gastroenterol Hepatol,2009
3. Drug absorption interactions between oral targeted anticancer agents and PPIs: is pH-dependent solubility the Achilles heel of targeted therapy?;Budha;Clin Pharmacol Ther,2012
4. pH-Dependent drug–drug interactions for weak base drugs: potential implications for new drug development;Zhang;Clin Pharmacol Ther,2014
5. Impaired drug absorption due to high stomach pH: a review of strategies for mitigation of such effect to enable pharmaceutical product development;Mitra;Mol Pharm,2013
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