Hepatobiliary Clearance Prediction: Species Scaling From Monkey, Dog, and Rat, and In Vitro–In Vivo Extrapolation of Sandwich-Cultured Human Hepatocytes Using 17 Drugs-Reference-Cited by-同舟云学术

Hepatobiliary Clearance Prediction: Species Scaling From Monkey, Dog, and Rat, and In Vitro–In Vivo Extrapolation of Sandwich-Cultured Human Hepatocytes Using 17 Drugs

Published:2017-09 Issue:9 Volume:106 Page:2795-2804
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Kimoto Emi,Bi Yi-An,Kosa Rachel E.,Tremaine Larry M.,Varma Manthena V.S.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference51 articles.

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4. Role of hepatic efflux transporters in regulating systemic and hepatocyte exposure to xenobiotics;Pfeifer;Annu Rev Pharmacol Toxicol,2014

5. Physicochemical property space of hepatobiliary transport and computational models for predicting rat biliary excretion;Varma;Drug Metab Dispos,2012

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