The role of fragment-based and computational methods in polypharmacology
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference93 articles.
1. From magic bullets to designed multiple ligands;Morphy;Drug Discov. Today,2004
2. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia;Roth;Nat. Rev. Drug Discov.,2004
3. Late-life dementias: does this unyielding global challenge require a broader view?;Montine;JAMA,2009
4. Designed multiple ligands. An emerging drug discovery paradigm;Morphy;J. Med. Chem.,2005
5. Multi-functional drugs for various CNS targets in the treatment of neurodegenerative disorders;Youdim;Trends Pharmacol. Sci.,2005
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