The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region
Author:
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology
Reference39 articles.
1. AKT/PKB signaling: navigating the network;Manning;Cell,2017
2. The PI3K/AKT pathway as a target for cancer treatment;Mayer;Annu. Rev. Med.,2016
3. Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer;Do;Invest. N. Drugs,2015
4. Effective drug combinations in breast, colon and pancreatic cancer cells;Jaaks;Nature,2022
5. Phase I trial of the PARP inhibitor olaparib and AKT inhibitor capivasertib in patients with BRCA1/2- and non-BRCA1/2-mutant cancers;Yap;Cancer Discov.,2020
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