Estrogen induces endometrial cancer cell proliferation and invasion by regulating the fat mass and obesity-associated gene via PI3K/AKT and MAPK signaling pathways

Author:

Zhang Zhenbo,Zhou Dongmei,Lai Yunli,Liu Yongjuan,Tao Xiang,Wang Qianqian,Zhao Guixu,Gu Hongqin,Liao Hong,Zhu Yaping,Xi Xiaowei,Feng Youji

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference34 articles.

1. Obesity, endogenous hormones, and endometrial cancer risk: a synthetic review;Kaaks;Cancer Epidemiol. Biomarkers Prev.,2002

2. Obesity and cancer: pathophysiological and biological mechanisms;Renehan;Arch. Physiol. Biochem.,2008

3. Estrogen and tamoxifen induce cytoskeletal remodeling and migration in endometrial cancer cells;Acconcia;Endocrinology,2006

4. Risk of exogenous estrogen therapy and endometrial cancer;Jelovsek;Am. J. Obstet. Gynecol.,1980

5. Cell proliferation in cancer prevention; effects of preventive agents on estrogen-related endometrial carcinogenesis model and on an in vitro model in human colorectal cells;Mori;Mutat. Res.,2001

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