MCAM/CD146 promotes tamoxifen resistance in breast cancer cells through induction of epithelial–mesenchymal transition, decreased ERα expression and AKT activation

Author:

Liang Yuan-Ke,Zeng De,Xiao Ying-Sheng,Wu Yang,Ouyang Yan-Xiu,Chen MinORCID,Li Yao-Chen,Lin Hao-Yu,Wei Xiao-Long,Zhang Yong-Qu,Kruyt Frank A.E.,Zhang Guo-JunORCID

Funder

Natural Science Foundation Committee

Major International Collaborative Research Project of NSFC

Guangdong Provincial Key Laboratory on Breast Cancer Diagnosis and Treatment Research

Natural science Foundation of Guangdong

Science and Technology Planning Project of Shantou City, Guangdong Province, China

Medical Scientific Research Foundation of Guangdong Province, China

Department of Education, Guangdong Government under the Top-tier University Development Scheme for Research and Control of Infectious Diseases

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference45 articles.

1. Treatment of estrogen receptor-positive breast cancer;Lumachi;Curr. Med. Chem.,2013

2. Adjuvant endocrine therapy for early breast cancer;Andreetta;Cancer Lett.,2007

3. Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group;Lancet,1998

4. Tamoxifen for breast cancer;Karn;J. Nepal Med. Assoc.,2010

5. Endocrine therapy resistance: current status, possible mechanisms and overcoming strategies;Chang;Anticancer Agents Med. Chem.,2013

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