Phase I and phase II xenobiotic biotransformation in cultures and co-cultures of adult rat hepatocytes

Author:

Rogiers Vera,Vandenberghe Yves,Callaerts André,Verleye Gino,Cornet Miranda,Mertens Karine,Sonck Walter,Vercruysse Antoine

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference41 articles.

1. Biological models as alternatives to animal experimentation;Benford;ATLA,1987

2. Isolation and culture of liver cells and their use in the biochemical research of xenobiotics;Suolinna;Med Biol,1982

3. Use of isolated and cultured hepatocytes for xenobiotic metabolism and cytotoxicity studies;Guillouzo,1986

4. Isolated hepatocytes as a suitable in vitro model for biotransformation and toxicity studies of xenobiotics;Rogiers,1988

5. Effect of culture age on drug metabolizing enzymes and their induction in primary cultures of rat hepatocytes;Suolinna;Biochem Pharmacol,1986

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