Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative-Reference-Cited by-同舟云学术

Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative

Published:1993-12 Issue:12 Volume:46 Page:2249-2267
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Clement Bernd,Schultze-Mosgau Marcus-Hillert,Wohlers Hanke

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference55 articles.

1. Arzneimittelwirkungen;Mutschler,1991

2. Biotransformation stark basischer funktioneller Gruppen durch Stickstoffoxidation. Hochschulsammlung Naturwissenschaft;Clement;Chemie Pharmazie,1985

3. The oxidation of benzamidines in vitro;Clement;Xenobiotica,1983

4. New aspects of the microsomal N-hydroxylation of benzamidines;Clement,1991

5. The in vitro oxygenation of N,N-diphenylguanidines;Clement;Xenobiotica,1993

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