A novel testosterone 6β-hydroxylase activity assay for the study of CYP3A-mediated metabolism, inhibition, and induction in vitro
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference25 articles.
1. Allosteric behavior in cytochrome P450-dependent in vitro drug–drug interactions: a prospective based on conformational dynamics;Atkins;Chemical Research in Toxicology,2001
2. Ethyl acetate extraction procedure and isocratic high performance liquid chromatography assay for testosterone metabolites in cell microsomes;Baltes;Journal of Chromatography B,1998
3. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein–dye binding;Bradford;Analytical Biochemistry,1976
4. Development of a non-high pressure liquid chromatography assay to determine testosterone hydroxylase (CYP3A) activity in human liver microsomes;Draper;Drug Metabolism and Disposition,1998
5. Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes;Eagling;British Journal of Clinical Pharmacology,1998
Cited by 26 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Insights into the development of pentylenetetrazole-induced epileptic seizures from dynamic metabolomic changes;Metabolic Brain Disease;2022-07-15
2. A dual functional probe for assessing human CYP450 3A5 and 3A enzymes bioactivities;Future Medicinal Chemistry;2019-11
3. Interspecies differences in metabolism of deoxypodophyllotoxin in hepatic microsomes from human, monkey, rat, mouse and dog;Drug Metabolism and Pharmacokinetics;2016-08
4. Assessment of cytochrome P450 inhibition and induction potential of lupeol and betulin in rat liver microsomes;Drug Metabolism and Personalized Therapy;2016-01-01
5. Meclizine, a pregnane X receptor agonist, is a direct inhibitor and mechanism-based inactivator of human cytochrome P450 3A;Biochemical Pharmacology;2015-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3