Indole phytoalexins-derived bis-indoles: Design, synthesis and in vitro antiproliferative evaluation

Author:

Budovská MarianaORCID,Michalková Radka,Mojžiš Ján

Funder

Vedecká grantová agentúra MŠVVaŠ SR a SAV

European Regional Development Fund

Ministerstvo školstva, vedy, výskumu a športu Slovenskej republiky

Agentúra na Podporu Výskumu a Vývoja

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference26 articles.

1. The phytoalexins from cultivated and wild crucifers: chemistry and biology;Pedras;Nat. Prod. Rep.,2011

2. A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase;Banerjee;Oncogene,2008

3. Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells;Izutani;Int. J. Oncol.,2012

4. Brassinin and its derivatives as potential anticancer agents;Chripkova;Toxicol. Vitro,2014

5. ROS-dependent anti-proliferative effect of brassinin derivative homobrassinin in human colorectal cancer Caco2 cells;Kello;Molecules,2014

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1. Indole derivatives as agrochemicals: An overview;Chinese Chemical Letters;2023-08

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