Total synthesis of peumusolide A, NES non-antagonistic inhibitor for nuclear export of MEK
Author:
Funder
Japan Society for the Promotion of Science
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference15 articles.
1. Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
2. Leptomycin B Inhibition of Signal-Mediated Nuclear Export by Direct Binding to CRM1
3. CRM1 is responsible for intracellular transport mediated by the nuclear export signal
4. Peumusolide A, unprecedented NES non-antagonistic inhibitor for nuclear export of MEK
5. Anticancer Activity of Isoobtusilactone A from Cinnamomum kotoense: Involvement of Apoptosis, Cell-Cycle Dysregulation, Mitochondria Regulation, and Reactive Oxygen Species
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