Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue

Author:

Miwa M,Ura M,Nishida M,Sawada N,Ishikawa T,Mori K,Shimma N,Umeda I,Ishitsuka H

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference21 articles.

1. Role of uridine phosphorylase for antitumor activity of 5′-deoxy-5-fluorouridine;Ishitsuka;Gann,1980

2. Tissue distribution of 5′-deoxy-5-fluorouridine and derived 5-fluorouracil in tumor-bearing mice and rats;Suzuki;Gann,1980

3. Comparative studies on the antitumor activity of fluorinated pyrimidines, 5′-DFUR, Tegafur, UFT and FUra, with various murine tumors;Miwa;Jpn J Cancer Chemother,1988

4. Uehara N, Baba H, Nitta K, et al. The therapeutic effect of orally administered 5′-deoxy-5-fluorouridine, 1-(2-tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil on experimental murine tumors. Gann 1985, 76, 1034–1041.

5. A comparative study between 5′-DFUR and Tegafur in recurrent breast cancer;Taguchi;Jpn J Cancer Chemother,1985

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3