EGFR-independent EGFR-mutant lung adenocarcinoma cells depend on Bcl-xL and MCL1 for survival

Author:

Hirai SachieORCID,Tada Makoto,Yamaguchi Miki,Niki Toshiro,Sakuma YujiORCID

Funder

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference15 articles.

1. Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer;Pao;Nat. Rev. Canc.,2010

2. Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer;Leonetti;Br. J. Canc.,2019

3. Overall survival with osimertinib in untreated, EGFR-mutated advanced NSCLC;Ramalingam;N. Engl. J. Med.,2020

4. Enhanced autophagy is required for survival in EGFR-independent EGFR-mutant lung adenocarcinoma cells, Lab;Sakuma;Invest,2013

5. Prolyl isomerase Pin1 promotes survival in EGFR-mutant lung adenocarcinoma cells with an epithelial-mesenchymal transition phenotype;Sakuma;Lab. Invest.,2016

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