Ethyl pyruvate inhibits proliferation and induces apoptosis of hepatocellular carcinoma via regulation of the HMGB1–RAGE and AKT pathways

Author:

Cheng Ping,Dai Weiqi,Wang Fan,Lu Jie,Shen Miao,Chen KanORCID,Li Jingjing,Zhang Yan,Wang Chengfen,Yang Jing,Zhu Rong,Zhang Huawei,Zheng Yuanyuan,Guo Chuan-Yong,Xu Ling

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference27 articles.

1. Molecular signatures associated with HCV-induced hepatocellular carcinoma and liver metastasis;De Giorgi;PLoS One,2013

2. Rapid long-lasting biochemical and radiological response to sorafenib in a case of advanced hepatocellular carcinoma;Gerardi;Oncol. Lett.,2013

3. High-mobility group box1 protein promotes neuroinflammation after intracerebral hemorrhage in rats;Lei;Neuroscience,2013

4. Inhibitory effects of ethyl pyruvate administration on human gastric cancer growth via regulation of the HMGB1–RAGE and Akt pathways in vitro and in vivo;Zhang;Oncol. Rep.,2012

5. The HMGB1/RAGE inflammatory pathway promotes pancreatic tumor growth by regulating mitochondrial bioenergetics;Kang;Oncogene,2013

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