T cell activation and lowered T regulatory cell numbers are key processes in severe major depressive disorder: Effects of recurrence of illness and adverse childhood experiences

Author:

Maes Michael,Zhou Bo,Rachayon Muanpetch,Jirakran Ketsupar,Sughondhabirom Atapol,Sodsai Pimpayao,Almulla Abbas F.

Publisher

Elsevier BV

Reference70 articles.

1. The physio-affective phenome of major depression is strongly associated with biomarkers of astroglial and neuronal projection toxicity which in turn are associated with peripheral inflammation, insulin resistance and lowered calcium;Al-Hakeim;J. Affect. Disord.,2023

2. T helper-1 activation via interleukin-16 is a key phenomenon in the acute phase of severe, first-episode major depressive disorder and suicidal behaviors;Almulla;J. Adv. Res.,2023

3. Brain-targeted autoimmunity is strongly associated with long COVID and its chronic fatigue syndrome as well as its affective symptoms;Almulla;MedRxiv,2024

4. Diagnostic and Statistical Manual of Mental Disorders (Fifth d.);American Psychiatric Association,2013

5. One experience with ‘lower’ or ‘higher’ intensity stressors, respectively enhances or diminishes responsiveness to haloperidol weeks later: implications for understanding drug variability;Antelman;Brain Res.,1991

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