N-acetylcysteine protects human periodontal ligament fibroblasts from pyroptosis and osteogenic differentiation dysfunction through the SIRT1/NF-κB/Caspase-1 signaling pathway

Author:

Chu Yi,Xu Yao,Yang Wanrong,Chu Kefei,Li Sihui,Guo Ling

Funder

Sichuan Provincial Administration of Traditional Chinese Medicine

Luzhou Science and Technology Bureau

Shaanxi Administration of Traditional Chinese Medicine

Southwest Medical University

Publisher

Elsevier BV

Subject

Cell Biology,General Dentistry,General Medicine,Otorhinolaryngology

Reference45 articles.

1. Dysregulation of inflammasomes in human dental pulp cells exposed to porphyromonas gingivalis and fusobacterium nucleatum;Aral;Journal of Endodontics,2020

2. N‐acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities;Bavarsad Shahripour;Brain and Behavior,2014

3. Casein kinase 1alpha governs antigen-receptor-induced NF-κB activation and human lymphoma cell survival;Bidère;Nature,2009

4. Periodontal inflammation-triggered by periodontal ligament stem cell pyroptosis exacerbates periodontitis;Chen;Frontiers in Cell and Developmental Biology,2021

5. Periodontal disease status among adults from South Africa—prevalence and effect of smoking;Chikte;International Journal of Environmental Research and Public Health,2019

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