Improved tropoelastin synthesis in the skin by codon optimization and nucleotide modification of tropoelastin-encoding synthetic mRNA

Author:

Golombek Sonia,Hoffmann Thomas,Hann Ludmilla,Mandler Markus,Schmidhuber Sabine,Weber Josefin,Chang Young-Tae,Mehling Roman,Ladinig Andrea,Knecht Christian,Leyens Johanna,Schlensak Christian,Wendel Hans Peter,Schneeberger Achim,Avci-Adali MeltemORCID

Funder

Eurostars

Eberhard Karls Universität Tübingen

Horizon 2020

Publisher

Elsevier BV

Subject

Drug Discovery,Molecular Medicine

Reference48 articles.

1. Delivery of synthetic mRNAs for tissue regeneration;Steinle;Adv. Drug Deliv. Rev.,2021

2. mRNA-based therapeutics--developing a new class of drugs;Sahin;Nat. Rev. Drug Discov.,2014

3. In vitro synthesis of modified mRNA for induction of protein expression in human cells;Avci-Adali;J. Vis. Exp.,2014

4. Current prospects for mRNA gene delivery;Yamamoto;Eur. J. Pharm. Biopharm.,2009

5. Biochemistry of the elastic fibers in normal connective tissues and its alterations in diseases;Uitto;J. Invest. Dermatol.,1979

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