Automated production of gene-modified chimeric antigen receptor T cells using the Cocoon Platform

Author:

Trainor NualaORCID,Purpura Kelly A.,Middleton Kevin,Fargo Karen,Hails Lauren,Vicentini-Hogan Michele,McRobie Chase,Daniels Raelyn,Densham Phil,Gardin PaulORCID,Fouks Michael,Brayer Hadar,Malka Rivka Gal,Rodin Anastasia,Ogen Tal,Besser Michal J.,Smith Tim,Leonard David,Bryan Adam

Publisher

Elsevier BV

Subject

Cancer Research,Transplantation,Cell Biology,Genetics (clinical),Oncology,Immunology,Immunology and Allergy

Reference36 articles.

1. Treatment of patients with metastatic cancer using major histocompatibility complex Class II-restricted T-cell receptor targeting the cancer germline antigen MAGE-A3;Lu;J. Clin. Oncol.,2017

2. First-in-human multicenter study of bb2121 anti-BCMA CAR T-cell therapy for relapsed/refractory multiple myeloma: updated results;Berdeja;J. Clin. Oncol.,2017

3. Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells;Kebriaei;J. Clin Invest.,2016

4. National Cancer Institute. CAR T Cells: Engineering Patients’ Immune Cells to Treat Their Cancers 2022 https://www.cancer.gov/about-cancer/treatment/research/car-t-cells (accessed May 4, 2023).

5. Global manufacturing of CAR T cell therapy;Levine;Mol. Ther. Methods Clin. Dev.,2017

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