Triplet (FOLFOXIRI) versus doublet (FOLFOX or FOLFIRI) backbone chemotherapy as first-line treatment of metastatic colorectal cancer: A systematic review and meta-analysis

Author:

Marques Rui Pedro,Duarte Gonçalo S.,Sterrantino Carmelo,Pais Helena Luna,Quintela António,Martins Ana Paula,Costa João

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference40 articles.

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2. Cetuximab plus FOLFIRINOX (ERBIRINOX) as first-line treatment for unresectable metastatic colorectal cancer: a phase II trial;Assenat;Oncologist,2011

3. Overal l response rate in STEAM, a randomized, open-label, phase 2 trial of sequential and concurrent FOLFOXIRI-bevacizumab vs FOLFOX-bevacizumab for the first-line treatment of patients with metastatic colorectal cancer;Bendell;ASCO Gastrointestinal Cancers Symposium,2016

4. First-line chemotherapy for mCRC-a review and evidence-based algorithm;Cremolini;Nat. Rev. Clin. Oncol.,2015

5. FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study;Cremolini;Lancet Oncol.,2015

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