Tetramethylpyrazine inhibits keratitis and neovascularization induced by corneal alkali burn by suppressing the TLR4/NF-κB pathway activation and NLRP1/NLRP3 inflammasomes in rats

Author:

Jiang Tao,Wang Chun-Yang,Chen Ying

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

Reference40 articles.

1. Safety and efficacy of the multitargeted receptor kinase inhibitor pazopanib in the treatment of corneal neovascularization;Amparo;Invest. Ophthalmol. Vis. Sci.,2013

2. Corneal neovascularization as a risk factor for graft failure and rejection after keratoplasty: an evidence-based meta-analysis;Bachmann;Ophthalmology,2010

3. Inhibition of angiogenesis, fibrosis and thrombosis by tetramethylpyrazine: mechanisms contributing to the SDF-1/CXCR4 axis;Cai;PLoS One,2014

4. Corneal neovascularization;Chang;Curr. Opin. Ophthalmol.,2001

5. MK2 inhibitor reduces alkali burn-induced inflammation in rat cornea;Chen;Sci. Rep.,2016

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