Updated Overall Survival Data and Predictive Biomarkers of Sintilimab Plus Pemetrexed and Platinum as First-Line Treatment for Locally Advanced or Metastatic Nonsquamous NSCLC in the Phase 3 ORIENT-11 Study

Author:

Yang Yunpeng,Sun Jiya,Wang Zhehai,Fang Jian,Yu Qitao,Han Baohui,Cang Shundong,Chen Gongyan,Mei Xiaodong,Yang Zhixiong,Ma Rui,Bi Minghong,Ren Xiubao,Zhou Jianying,Li Baolan,Song Yong,Feng Jifeng,Li Juan,He Zhiyong,Zhou Rui,Li Weimin,Lu You,Zhou Hui,Wang Shuyan,Sun Luyao,Puig Oscar,Mancao Christoph,Peng Bo,Fang Wenfeng,Xu Wei,Zhang Li

Publisher

Elsevier BV

Subject

Pulmonary and Respiratory Medicine,Oncology

Reference29 articles.

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2. Pembrolizumab plus chemotherapy for squamous non-small-cell lung cancer;Paz-Ares;N Engl J Med,2018

3. Evaluation of TMB in KEYNOTE-189: pembrolizumab plus chemotherapy vs placebo plus chemotherapy for nonsquamous NSCLC;Garassino;J Thorac Oncol,2019

4. LBA80 Pembrolizumab (pembro) plus platinum-based chemotherapy (chemo) for metastatic NSCLC: tissue TMB (tTMB) and outcomes in KEYNOTE-021, 189, and 407;Paz-Ares;Ann Oncol,2019

5. Safety and activity of sintilimab in patients with relapsed or refractory classical Hodgkin lymphoma (ORIENT-1): a multicentre, single-arm, phase 2 trial;Shi;Lancet Haematol,2019

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